Diets Can improve NAF Findings

Changes in diet and/or the use of dietary supplements are considered to possibly have an impact on breast cancer occurrence and can potentially change the cytology or the presence of biomarkers in NAF.

A study of the effect of dietary intervention in 71 women over a one year period was conducted. The probability of obtaining a cellular NAF cytology increased with dietary fat intake, reaching over 7-fold increase for the highest to lowest quartile of fat intake. Furthermore, cellular NAF decreased with increasing plasma levels of dietary supplement antioxidants, lutein and alpha-carotene.

Additional studies are ongoing in collaboration with the National Cancer Institute to look at the effect of other interventions, using NAF sample collection and analysis of cytology and molecular biomarkers as study end points, and the Company believes the successful outcome of one or more of these studies could increase the use of NAF analysis.